The prevalence of DH was found to vary from about 5 to 62% owing to the use of different diagnostic and measuring tools and age groups in the published literature, with the best average estimate of 34% worldwide [3]. Ingredients *Potassium Nitrate Another study by Hines et al. 2018;75:1221. Treatments provided to the patients were OTC dentifrices marketed with the claim of immediate pain relief in DH. This trial was registered in an ICMJE approved registry at https://clinicaltrials.gov/) under protocol Identifier: NCT04249336 [19] following the CONSORT guidelines [20] for parallel-group randomized trials after approval from the Institutional Review Board of Dow University of Health Sciences with reference no. Colgate Total with stannous fluoride also offers more benefits than ever before, including sensitivity relief, improved enamel strength* and odor neutralization* (*based on in vitro studies).Colgate Total Advanced Whitening is a tooth whitening toothpaste that provides stain removal and prevention. For instant relief, just apply directly to the sensitive tooth with finger tip and gently massage for one minute. Dent Health Curr Res. 2009; 20 (Spec Iss): 1722. Colgate Sensitive Pro-Relief efektywnie i szybko znosi nadwraliwo zbw, zamyka kanaliki zbinowe w ktrych s zakoczenia nerww, dziki czemu blokuje bl. Shrimathi S. Effect of BiominF, NovaminR, Argin and nanohydroxy particles containing dentifrices on dentine hypersensitivity and gingivitis among 3544 years aged population of Madurai district: a randomized controlled trial (RCT). ^Vs novamin/sodium fluoride technology and stannous fluoride/sodium fluoride technology (p<0.05). Follow the directions for use. The statistically significant change in mean scores of DH was observed with FCPS with p<0.05 relative to baseline for sustained relief from DH at follow-ups on day 3, week 2, week 4, and week 6, using clinical parameters of SCASS and VAS. YYYY Colgate-Palmolive Company. 2. Apotekets varuid 29483 Varunummer 207000 Kategori Tandkrm, Ilningar i tnderna Varumrke It revealed an immediate improvement with strontium acetate more than Pro-argin on SCASS. BMC Oral Health Participants analyzed per group were more than thirty fulfilling the requirement of Holland's guidelines for conducting clinical trials for the management of DH [42]. Helps repair teeth by forming a mineral layer that re-constructs the sensitive part of the tooth, with regular use; Seals the open nerve channels for instant relief, and helps prevent sensitivity from re-occurring; Plus the freshness you trust from Colgate Colgate Sensitive Pro Relief can be applied directly to the affected area for almost instant relief. Cunha-Cruz J, Wataha JC. [33] again reported a 54% clinical reduction in DH with Pro-argin in eight weeks clinical trial using SCASS. Nathoo S, Delgado E, Zhang YP, DeVizio W, Cummins D, Mateo LR: Comparing the efficacy in providing instant relief of dentine hypersensitivity of a new toothpaste containing 8.0% arginine, calcium carbonate, and 1450 ppm fluoride to a benchmark desensitizing toothpaste containing 2% potassium ion and 1450 ppm fluoride and to a control toothpaste with 1450 ppm fluoride: A three-day clinical study in New Jersey, USA. However, Pro-argin showed more clinical improvement in air blast and mechanically stimulated DH compared to 8% strontium acetate, as shown in Tables 4 and 5. Written consent was obtained from all participants to participate in the six-week clinical trial. Favaro Zeola L, Soares PV, Cunha-Cruz J. Dentin hypersensitivity treatments work in one of two ways. A total of 140 participants were initially enrolled and randomised into the four treatment arms, with thirty-five in each group. A previously published study by Samueli et al. It improves gum health and helps reduce factors that contribute to gum recession, a leading cause of tooth sensitivity. Provides 24/7 sensitivity protection. For instant relief, apply directly to each sensitive tooth surface and massage for one minute, up to twice a day. Soft tissues were isolated with cotton rolls, and adjacent teeth were isolated with cotton pellets. FCPS was incorporated in OTC dentifrice with calcium, low contents of fluoride, and high contents of phosphate ions. Gillam D, Hill R, Samueli A. Bioactive glasses in the management of dentine hypersensitivity: a review. Prevalence of dentin hypersensitivity: systematic review and meta-analysis. Participants were asked to pick up the envelope from the box. A study evaluating the efficacy of strontium acetate relative to arginine-based dentifrices was conducted by West et al. Colgate SENSITIVE INSTANT Relief Repair & Prevent Toothpaste for the daily oral care of patients with dentine hypersensitivity and gum problems. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data. Compared to stannous fluoride/sodium fluoride and novamin/sodium fluoride. However, there is a substantial possibility that these fluoridated dentifrices can reduce DH. Clinical Efficacy Of BioMin F, Colgate Sensitive Pro-Relief And Sensodyne Rapid Action Dentifrices In DH The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Click here. Terms and Conditions, Colgate Sensitive Pro-Relief (Toothpaste): 1.9 out of 5 stars from 91 genuine reviews on Australia's largest opinion site ProductReview.com.au. J Dent Res. The secondary objective of the study was to compare the clinical efficacy of Pro-argin, strontium acetate, and FCPS for immediate and sustained treatment response in DH that was measured on SCASS as a primary outcome measure and VAS as secondary outcome measure at efficacy intervals of one minute, day-three, week two, four and six. A toothbrushing demonstration model from Nissin Company specification [PE-ORT002] was used to explain to the study participants about applying OTC dentifrices for one minute with the participant's finger. Dentinal tubules occluded by bioactive glass-containing toothpaste exhibit high resistance toward acidic soft drink challenge. Customers also search toothpaste colgate sensitive colgate enamel colgate pro relief colgate pain relief 2017;62(2):18691. 2019;81:16. With its unique Pro-Argin technology, this sensitive toothpaste will give you instant* relief from sensitivity as it helps to seal and repair the sensitive areas of your teeth. Delivering better oral health - An Evidence-based toolkit for prevention. Holland GR, Narhi MN, Addy M, Gangarosa L, Orchardson R. Guidelines for the design and conduct of clinical trials on dentine hypersensitivity. Lg i kurv. Fordeler Colgate SENSITIVE INSTANT Relief tannkrem er klinisk dokumentert virke i lpet av sekunder samtidig som den beskytter tannen mot at smerten skal komme tilbake. Colgate Sensitive Pro Relief was compared to a leading brand of desensitizing toothpaste containing stannous fluoride in a laboratory study, with confocal laser scanning microscopy and a novel imaging program used to qualify dentinal tubule occlusion. Colgate Sensitive Pro Relief offers a solution that is clinically proven to relieve sensitivity pain. Besides, these findings of the current study could be related to previously conducted clinical trials indicating the better clinical effectiveness of Pro-argin than strontium acetate against air-blast and tactile stimulus after three days and one week of application [30, 31]. J Oral Rehabil. compared the Pro-Argin formulation with a calcium sodium phosphosilicate toothpaste, demonstrating 88% versus 50% occlusion respectively. Zang P, Shaw D. A randomized clinical study to evaluate the efficacy of an 8%(w/w) strontium acetate dentifrice in providing relief from dentinal hypersensitivity. The benefits are backed by over a decade of clinical research, summarized as follows. Colgate Sensitive Pro-Relief works by plugging the channels to block tooth sensitivity and with regular use, it builds a long-lasting protective barrier that acts like a seal against sensitivity. For lsting relief, apply to a gentle toothbrush making sure to brush all sensitive areas of the teeth twice daily. The outcomes are in concordance with the previous studies conducted by Layer and Hughes [26], Zang and Shaw [27], and Mason et al. YES Somewhat No BMC Oral Health 21, 498 (2021). J Clin Dent 20 (2009), special issue 17-22, 3. Colgate Sensitive Instant Relief Repair & Prevent Toothpaste starts blocking sensitivity pain instantly*. All rights reserved. The Gum Health Physical is a new interactive digital tool you can use to quickly evaluate your patients in-office, and give them a personalized report they can use at home. Mockdeci H, Polonini H, Martins I, Granato A-P, Raposo N. Evaluation of ex vivo effectiveness of commercial desensitizing dentifrices. J Clin Exp Dent. Colgate SENSITIVE INSTANT Relief Repair & Prevent toothpaste with PRO-ARGIN Technology and Zinc provides clinically proven instant* and lasting sensitivity relief1-2 plus lasting gum protection3. Martins C, Firmino R, Riva J, Ge L, Carrasco-Labra A, Brignardello-Petersen R, et al. Dent Health Curr Res. blokerer jeblikkeligt smerter fra isninger. Schiff T, Delgado E, Zhang Y, Cummins D, DeVizio W, Mateo L. Clinical evaluation of the efficacy of an in-office desensitizing paste containing 8% arginine and calcium carbonate in providing instant and lasting relief of dentin hypersensitivity. The relief from sensitivity offered by Colgate Sensitive Pro Relief is proven to last. When it begins to interfere with oral hygiene, it can also lead to poor oral health outcomes. The study's primary objective was to investigate pain relief in one minute with Pro-argin and strontium acetate in DH measured on SCASS as a primary outcome measure and VAS as a secondary outcome measure. Colgate Sensitive Pro Relief was found to achieve 91% dentin occlusion, compared to 67% for the stannous fluoride toothpaste. https://doi.org/10.17352/2394-8418.00003. Most sensitive toothpastes primarily numb the discomfort, whereas Colgate Sensitive Pro-Relief works to relieve sensitivity by plugging the channels that lead to sensitive tooth nerves. Benefits: Colgate Sensitive Prevent and Repair is clinically proven to provide superior relief vs Sensodyne Extra Whitening at 8 weeks1 Long-lasting relief from hypersensitivity with continued use Superior sensitivity relief at 8 weeks vs the leading Sensodyne toothpaste variant 1 While your patients may have dentine hypersensitivity in common, their oral care needs will vary. (Table 1) (Fig. Matranga D, Matera F, Pizzo G. Evaluating the statistical methodology of randomized trials on dentin hypersensitivity management. DH most commonly involves the facial surfaces of maxillary and mandibular permanent teeth. Manage cookies/Do not sell my data we use in the preference centre. There was no statistically significant treatment difference between the two (p=0.499). J Dent. 2. Venkataramana S, Jeyaraman SK, Kothimbakkam SSK, Chellathurai BNK. Helps restore natural whiteness of teeth. 1997;24(11):80813. Colgate SENSITIVE INSTANT Relief tannkrem med Pro-Argin teknologi gir umiddelbar* og langvarig smertelindring av ising i tennene. We observed the varying treatment response at different efficacy intervals that could be due to the varying degree of patient's response to pain-provoking stimuli in DH. For lsting relief, apply to a gentle toothbrush making sure to brush all . They reported more clinical efficacy with BioMin than Pro-argin reduction in air-blast stimulated DH on VAS after one month [39]. Privacy See patient relevant information on Colgate.com. However, we can conclude that both Pro-argin and strontium acetate-based dentifrices disrupt the pathophysiology of DH and are effective for immediate pain relief even one minute after application on sensitive teeth. Mode of action studies on a new desensitizing dentifrice containing 8.0% arginine, a high cleaning calcium carbonate system and 1450 ppm fluoride. * For instant relief apply to the sensitive tooth with a figure tip and gently massage for one minute. [18] in a meta-analysis in 2020. Clin Cosmet Investig Dent. All participants were instructed to dry the tooth surface with the cotton ball and apply a paste of about half-inch length on the dried surface for one minute, then brush the teeth twice daily after breakfast and before sleep as per directions demonstratedon the study model. 2013;41(2):18794. [10] examined the evidence for strontium acetate and Pro-argin in 2018, and their findings depicted low quality of evidence for strontium acetate on the Grading of Recommendations, Assessment, Development, and Evaluations system (GRADE). & Farooqui, W.A. Network meta-analysis on the effect of desensitizing toothpastes on dentine hypersensitivity. Arginine, Calcium Carbonate, Aqua, Sorbitol, Aroma, Poloxamer 407, Sodium Monofluorophosphate, Cocamidopropyl betaine, Zinc oxide, Benzyl Alcohol, Cellulose Gum, Zinc Citrate, Sodium Bicarbonate, Tetrasodium Pyrophosphate, Xantham Gum, Sodium Saccharin, Sucralose, Limonene, CL77891, 1. HOW LONG CAN A PATIENT USE Colgate SENSITIVE INSTANT Relief Repair & Prevent? In our study, patient compliance related to the recommended time of application and method of the application provided by doctors was controlled by subjecting multiple efficacy intervals and different methods for assessment of the change in pain scores due to DH. J Clin Periodontol. *with direct application and daily brushing. compared the Pro-Argin formulation with a calcium sodium phosphosilicate toothpaste, demonstrating 88% versus 50% occlusion respectively. Akber A, Ali NS, Shabbir S, Wahid U, Farooqui WA. SCASS and VAS were introduced on each visit as primary and secondary outcome measures, respectively. Therefore, in the current study, we used a dental explorer and the air blast and water jet stimuli from the triple syringe of the dental unit for testing DH to control the subjective variations in treatment response. Hu ML, Zheng G, Lin H, Yang M, Zhang YD, Han JM. Holland G, Narhi M, Addy M, Gangarosa L, Orchardson R. Guidelines for the design and conduct of clinical trials on dentine hypersensitivity. Last updated on May 11, 2021. Colgate Sensitive Plus Toothpaste developed for sensitive teeth provides sensitivity protection And helps in Enamel Repair, Cavity . Clinically proven lasting relief for 8 weeks. Clinical efficacy of BioMin F, Colgate sensitive pro-relief and Sensodyne rapid action dentifrices in DH [Internet]. J Dent. * with direct application and daily brushing Benefits Exclusive Pro-Argin formula Prevents sensitivty coming back 0:00 / 0:30 Colgate Sensitive Pro-Relief Challenge Advert April 2012 178,990 views Mar 29, 2012 Take the Colgate Sensitive Pro-Relief Challenge to Show more 15 Dislike Share. Pro-Argin showed a greater reduction in DH with mean scores of (1.340.68) (4.201.70) (3.052.17) followed by strontium acetate (1.570.81) (4.651.87) (3.751.97) on SCASS and VAS for mechanical and water jet stimuli, one minute after application. Int J Dent. Colgate Sensitive Pro-relief Instant Relief. 1 Nathoo et al. Gillam D, Talioti E. The Management of Dentine Hypersensitivity. PubMed Based on the synthesis of study results, we can conclude that Pro-argin in Colgate Sensitive Pro-relief and 8% strontium acetate in Sensodyne Rapid Action both are effective for pain relief in one minute after application in DH with better immediate treatment response of Pro-argin than strontium acetate. Colgate-Palmolive Company 2018. * For instant relief, apply directly to the sensitive tooth with finger tip and gently massage for 1 minute. 2009;22(Spec No. [8] that demonstrated the inherent ability of chemical interaction between arginine and type 1 collagen molecules in the salivary alkaline PH, thus resulting in endogenous calcium phosphate deposition on exposed dentinal tubules. These measures facilitated behaviour modification together with the promotion of knowledge and understanding in the society about DH. 2019;40(10):6537 (quiz 8). Internal report 2018, 5. 2020;99(5):51422. Significantly greater sensitivity reduction with twice - daily brushing compared to control toothpaste with potassium ions. 4.2 5 0 221 221 Colgate Sensitive Pro-Relief Enamel Rebuild toothpaste helps instantly repair sensitive teeth and provides lasting protection against hypersensitivity. 2016;3(1):0504. Therefore, the first null hypothesis was that mean scores for pain due to DH among different treatment groups for immediate relief remain. Benefits. SA was the principal investigator and has contributed to design, data acquisition, analysis, and interpretation, and drafted the manuscript. Both treatments showed clinically and statistically significant (p<0.001) relief in pain due to DH relative to baseline on immediate post-treatment observation, as shown in Table 3. Made by one of the best-known oral care companies in Australia, it has been clinically proven to provide both instantaneous and lasting relief from sensitivity, whilst also: Fighting cavities. However, Pro-argin formulation showed 8% more improvement in clinical symptoms of DH than strontium acetate formulation one minute after application. Baseline scores were recorded to measure the intensity of pain due to DH on SCASS with scores2 [22] against air blast stimulus with a triple syringe of the dental unit and on a linear VAS of 10cm length with scores4cm [23], against mechanical stimulus with a dental probe and water jet stimulus with a triple syringe. The strength of this study was that participants were randomised into four treatment groups to generalise the results for the population [32]. After six weeks, FCPS-based dentifrices showed greater clinical efficacy with mean scores (1.801.73) than other treatment arms for waterjet stimulated DH. Colgate Sensitive PRO-Relief Provides clinically proven, everyday protection from painful sensitivity. There was statistically no significant difference in the baseline characteristics of gender, age, baseline mean scores of clinical parameters of SCASS, and VAS used for mechanical and water jet stimuli between the four treatment groups (p>0.05). Google Scholar. Dentifrices were removed carefully after one minute of undisturbed application by rinsing the air lightly with an air syringe, and the subject was asked to spit. Therefore, this trial was planned to investigate the clinical efficacy of Pro-argin and strontium acetate for immediate pain relief in DH after one minute of topical application to fill the research gap associated with limited published evidence and risk of bias in selection, performance, attrition, and reporting as predicted by Pessoa et al. Anyone you share the following link with will be able to read this content: Sorry, a shareable link is not currently available for this article. da Cruz LPD, Hill RG, Chen X, Gillam DG. Work with Colgate Professional to help provide better oral care to your patients. COLGATE. Colgate Sensitive Instant Relief Repair & Prevent tandkrm ger dig kliniskt bevisad lngvarig lindring mot ilningar i tta veckor nr du anvnder den tv gnger om dagen. Not all desensitizing toothpastes perform equally well. Gentle whitening formula. Colgate Sensitive Pro-Relief toothpastes have been formulated to provide instant and lasting relief from the pain associated with sensitive teeth. These findings were similar to a previous study conducted by Schiff et al. Participants were recalled at interim efficacy intervals of three days, two weeks, four weeks, and six weeks for assessment of sustained relief. These findings were similar to a previous study conducted by Schiff et al. *Fr omedelbar lindring ska du applicera direkt p den knsliga . was used for statistical analysis. 2016;27(4):916. 2017;30(4):2216. They don't. The sensitive toothpaste remineralises tooth enamel for more resistance against acid attacks. Pak Oral Dent J. SHOULD A PATIENT CONTINUE USING Colgate SENSITIVE INSTANT Relief Repair & Prevent TOOTHPASTE ONCE THE DENTINE SENSITIVITY HAS GONE? Learn more about caries in children from the resources provided on this page. Hu M-L, Zheng G, Zhang Y-D, Yan X, Li X-C, Lin H. Effect of desensitizing toothpastes on dentine hypersensitivity: a systematic review and meta-analysis. We discuss how this innovative technology works to provide patients with rapid and long-lasting relief from dentin hypersensitivity. The Pro-Argin technology repairs sensitive areas of the teeth for instant* and long-lasting sensitivity pain relief. 4Intervention D denotes Colgate Total. Colgate Sensitive Instant* Relief Enamel Repair Toothpaste gives you clinically proven lasting relief** from sensitivity for 8 weeks when you use it twice a day. Colgate Sensitive Pro-Relief Whitening Toothpaste provides clinically proven instant and lasting relief for sensitive teeth. Get the best deals for COLGATE Sensitive Pro Relief Complete Protection Toothpaste 110g. However, they also suggested further comparative evaluations of two dentifrices with large sample sizes as limited scientific evidence was found in previous studies [16]. 0. All the treatment groups subjected to testing in the present study revealed a considerable clinically significant symptomatic reduction in DH relative to the pre-treatment condition that was also statistically significant. Builds a protective barrier that acts like . Get the freedom to forget about tooth sensitivity with Colgate Sensitive Pro-Relief Complete Protection Toothpaste. Table 6 presents the change in the mean scores on VAS against waterjet stimulus from baseline to subsequent efficacy interval within each treatment arm. 2012;12(3):2208. J Dent. Lasting relief with 2x daily continued brushing. Elsevier; 2015. p. 3344. In vitro analysis suggested that FCPS-based dentifrice enabled the slow and sustained release of fluoride contents, resulting in more stable fluorapatite crystals in saliva [14, 15]. The maximum sampling time was 15min. In addition, they were responding to air-blast stimulus on the Schiff cold air sensitivity scale (SCASS) with scores2 [22]. The probable reason for variations between this clinical trial and previously conducted studies could be attributed to racial or ethnic differences between the conducted trials. Colgate-Palmolive Company 2018. Oral dentifrices were provided to the subject free of cost. Based on the outcomes of previous systematic reviews and meta-analysis, the rationale of the present study was to substantiate the claim of immediate pain relief after one-minute application in DH by non-invasive surface application of OTC dentifrices containing Pro-arginin Colgate Sensitive Pro-Relief, and 8% strontium acetate in Sensodyne Rapid Action and other objective was the comparative evaluation of the clinical efficacy of three technologies, BAG-based FCPS in BioMinR F, Pro-argin, and 8% strontium acetate at efficacy intervals of day three, week two, four and six for sustained inhibition of painful stimulus provoking DH as all three are dentinal tubular occluding dentifrices. who examined FCPS and Pro-argin formulations in 2018. Gently removes stains and helps restore the natural whiteness of your teeth. In contrast, there was a significant (p<0.001) reduction of 61.1% with FCPS, 60.1% with Pro-argin, 53.4% with 8% strontium acetate, and 25% with NaF-based dentifrices relative to baseline after subsequent six weeks of application observing sustained relief from DH on SCASS. 2019;88:103170. Google Scholar. Compend Contin Educ Dent. Colgate Sensitive Pro-Relief works by plugging the channels to block tooth sensitivity and with regular use, it builds a long-lasting protective barrier that acts like a seal against sensitivity. Madurai: Best Dental Science College; 2020. J Clin Dent. J Clin Dent. Mintsmak. Springer Nature. Though all bioactive agents have a significant treatment effect in reducing DH, there is currently no consensus on the unequivocal efficacy of any product or bioactive agent used for managing the condition due to huge variations and heterogeneity in the conduct of clinical trials on DH [6]. Colgate SENSITIVE INSTANT Relief Repair & Prevent Toothpaste is an everyday toothpaste. Find products and services. YYYY Colgate-Palmolive Company. Book A total of 140 met the eligibility criteria with at least two sensitive teeth anterior to molars due to erosions or abrasions with or without an associated gingival recession. Pro-Argin Technology with arginine and an insoluble calcium compound, zinc and 1450ppm fluoride. These dentifrices were extracted in a plain tube by the dental assistant from commercial packing and labelled with treatment codes to keep the principal investigator and participants blinded at the time of treatment assignment. Identifier NCT 04249336. Colgate Sensitive Pro Relief Whitening Toothpaste 75ml tube (Pack of 4) Instant and Lasting Relief Clinically Proven with Active Ingredients We have a surprise for you Find out all personalised promo codes that you are eligible for. Explore the videos and articles found on this page to assist in better oral care. 2020;99(5):51422. It effectively occludes open dentine tubuli instantly* and builds a strong calcium-rich layer that ensures long-lasting relief from the pain of sensitivity.1,2 The protective layer remains strong even after exposure to acid attacks.3, of respondents confirmed reduced dentine hypersensitivity with Colgate SENSITIVE INSTANT Relief Repair & Prevent toothpaste6,, of respondents were happy with their dentists recommending Colgate SENSITIVE INSTANT Relief Repair & Prevent toothpaste6,, of respondents noticed long-lasting and instant* relief when brushing with Colgate SENSITIVE INSTANT Relief toothpaste7,, Colgate SENSITIVE PRO-Relief has been rebranded to Colgate SENSITIVE INSTANT Relief. Cookies policy. Exclusive Pro-Argin formula. Can be used after the Colgate Sensitive Pro-Relief Desensitizing Paste. It has stannous fluoride as an active ingredient. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. A randomised clinical trial on the efficacy of 5% fluorocalcium phosphosilicate-containing novel bioactive glass toothpaste. Dentifrices-containing Pro-argin showed a significant reduction in DH with mean scores of (3.052.17) followed by strontium acetate (3.751.97) followed by FCPS (5.301.83) one minute after application. Tel: +381 (0)21 452-910, +381 (0)21 420-758. OTC dentifrices were applied and massaged gently with the applicator on at least two sensitive teeth per subject at two different sites, including cementoenamel junction and exposed dentinal surface, by the doctor in the office during the first visit. Another study by Vu Pham and Anh Nguyen reported clinical improvement in DH by 38.9% on SCASS and 40.2% on VAS for mechanical stimulated DH immediately after application of Pro-argin [25]. This study investigated the relief from pain in DH in one minute after applying over the counter (OTC) dentifrices with Pro-Argin and strontium acetate and directly compared them with fluoro-calcium phospho-silicate (FCPS)-based dentifrices for immediate and sustained inhibition of painful stimulus provoking DH. J Clin Dent. 2009;22:3A-7A. Colgate SENSITIVE INSTANT Relief Repair & Prevent Toothpaste delivers instant* and long-lasting sensitivity relief plus gum protection. Our study included an Asian population, and most of the published literature was associated with the Caucasian population.
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